Complete Wordpress MU install

I have installed wordpress mu on my server. The install has gone well but there are a number of server setting changes which need making. I also want to be able to create unique domain names rather than have subdomains. There is a plug in 'wordpress mu domain mapping' which enables this. The job then is to get the script running properly by changing the server settings and installing and activating the domain mapping script so all I have to do is click, and get another blog set up. I have added the two readme files. Don't think this is a big task particularly if you have installed this before. If you want to see where I have got to or would like more info let me know.